Studies Reignite Debate over Avastin in Breast Cancer (CME/CE)

(MedPage Today) — Women with HER2-negative metastatic breast cancer had significantly higher rates of pathologic complete response when bevacizumab was added to neoadjuvant chemotherapy, two large clinical trials showed.

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Do-It-Yourself HPV TestHelps Screen for Cervical Cancer (CME/CE)

(MedPage Today) — Patient-collected specimens for human papillomavirus DNA testing detected precancerous cervical lesions with accuracy comparable to that of cytology-based Pap screening and visual inspection, data from screening studies showed.

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BRCA Mutations Also Play Good Role in Ovarian Cancer (CME/CE)

(MedPage Today) — Inherited mutations in the BRCA1 and BRCA2 genes, known to increase the risk of ovarian cancer, appear, paradoxically, to improve survival, researchers reported.

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ER Presentation Not the End for Colon Cancer Patients

SAN FRANCISCO (MedPage Today) — Curative therapy is still a possibility, even if a colon cancer patient is seen for the first time in the emergency department with acute symptoms, researchers said here.

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Extended Lymph Node Excision Feasible in Gastric Cancer

SAN FRANCISCO (MedPage Today) — In patients with gastric cancer, laparoscopic gastrectomy that includes removal of lymph nodes outside the immediate area around the stomach offered “excellent” margin status and node retrieval, researchers reported here.

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Drug Slows Progress of Prostate Cancer (CME/CE)

(MedPage Today) — Men with early prostate cancer had significantly less disease progression when treated with dutasteride (Avodart) as part of active surveillance, results of a randomized trial showed.

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Skipping Surgery in Early Esophageal Cancer May Be OK (CME/CE)

SAN FRANCISCO (MedPage Today) — Non-surgical therapies for stage 0-IA squamous esophageal cancer may be a viable alternative treatment that also provides a chance for organ preservation, according to a Japanese study.

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Bortezomib OK’d for SQ Delivery

(MedPage Today) — Subcutaneous administration of bortezomib (Velcade) has received FDA approval for both of the drug’s currently recognized indications, its manufacturer said.

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Cardiac Risk Higher for Women Getting Radiation

SAN FRANCISCO (MedPage Today) — Women undergoing radiation therapy for esophageal cancer appear to be at greater risk of cardiac complications than men, researchers reported here at the Multidisciplinary Gastrointestinal Cancers Symposium.

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Gastric Ca Survival Rates Down, Chemo Use Up

SAN FRANCISCO (MedPage Today) — A decline in survival rates in stage IV gastric cancer coincides with the increased use of chemotherapy rather than radiation and surgery, researchers found.

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